EINSTEIN PE
EINSTEIN PE is a unique trial evaluating the efficacy and safety of Xarelto® in a simple fixed-dose regimen for the initial and continued treatment of patients with acute symptomatic PE. The main objective of EINSTEIN PE is to determine whether Xarelto® is at least as effective as LMWH/VKA in the treatment of patients with acute symptomatic PE with or without symptomatic DVT.
The EINSTEIN PE trial completed in October 2011 and results will be reported in 2012.
The EINSTEIN PE trial completed in October 2011 and results will be reported in 2012.
- Efficacy
- The ability of a drug to produce the desired effect.
- Deep vein thrombosis
- A blood clot in a deep vein, usually resulting from damage to the vein or blood flow slowing down or stopping. Usually DVTs are found in the leg, but can also be in the arm. Distal DVTs are found in deep veins of the calf, and are the most common type of DVT. Proximal DVTs are found in the legs above the calf muscle up to the waist.
- Pulmonary embolism
- A potentially fatal condition caused by a blood clot blocking a vessel in the lung: usually the clot originates from a DVT in the legs. PE can result in permanent lung damage.
